Lyme disease can be a life-altering condition. Many people experience ongoing symptoms even after completing traditional antibiotic treatment. Chronic fatigue, joint pain, brain fog, and digestive problems are just some of the lingering effects. One overlooked factor in recovery is gut health.

Most Lyme disease sufferers go through long courses of antibiotics to kill the infection. While killing off the bacteria is necessary, this type of allopathic treatment protocol (and overuse of pharmaceutical antibiotics) may have reduced some of the harmful bacteria but have wiped out the beneficial ones that are there to keep the digestive system and immune system in check. This imbalance has led to gut-related issues, inflammation, and a weakened body. While our LP2 does not destroy the microbiome, chronic Lyme disease sufferers, (Often desperate for relief) that have often gone down the route of traditional pharmaceutical antibiotics will greatly benefit from adding our uniquely powerful LP3 Probiotic. A high-quality probiotic, paired with the Pre and Postbiotics in our LP3 Probiotic formula, can help restore gut health, strengthen immunity, and ease symptoms caused by Lyme and its treatments. Unlike traditional probiotics that rely on freeze-dried bacteria, this liquid formula contains live, naturally fermented strains and their postbiotics, making them easier for the body to absorb and use.

Why Gut Health Matters in Lyme Disease

The Gut-Immune Connection

The gut is home to nearly 70% of the immune system. A balanced gut microbiome helps regulate immune responses, prevents infections, and reduces inflammation. When Lyme disease and antibiotics disrupt this balance, the immune system struggles to function properly, leading to:

• Weakened immunity – making the body more vulnerable to other infections.
• Increased inflammation – worsening joint pain, fatigue, and cognitive issues.
• Poor digestion – causing bloating, diarrhea, constipation, and nausea.

Reintroducing beneficial bacteria through a potent probiotic supplement helps rebalance the microbiome, strengthen immunity, and reduce persistent inflammatory symptoms after Lyme treatment.

The Problem with Traditional Probiotics

Many probiotic supplements contain freeze-dried bacteria that struggle to survive stomach acid and colonize the gut effectively. LP3’s Probiotics, however, provides a liquid ecosystem of 11 live probiotic strains that remain active from the moment you take them. This makes them 16 times more effective at reaching the intestines, where they are needed most. Including naturally occurring postbiotics, this supplement also delivers pre-digested
nutrients that help gut bacteria flourish. This approach ensures faster and longer-lasting benefits, making it an ideal choice for Lyme sufferers looking for real relief.

How Each Probiotic Strain Helps Lyme Disease Symptoms

The gut microbiome is critical in Lyme disease recovery, affecting digestion, inflammation, immune function, and even brain health. Each strain in LP3 Probiotics (and our POWER OF 3 special pre- pro-post biotic combination) offers unique benefits that help counteract the effects of antibiotic use, chronic infection, and immune system dysregulation.

Lactobacillus fermentum – Reduces Inflammation & Supports Antioxidant Defense (4)

Chronic inflammation is one of the biggest challenges in Lyme disease. Lactobacillus fermentum helps by:

• Producing antioxidants that neutralize free radicals, reducing oxidative stress linked to Lyme infections.
• Lowering systemic inflammation, which can relieve joint pain, brain fog, and gut irritation.
• Strengthening the gut lining and preventing leaky gut syndrome are common issues after prolonged antibiotic use.

This strain is key in modulating immune responses, helping the body fight infection without overreacting and causing more harm.

Bacillus subtilis – Restores Gut Microbiome & Produces Digestive Enzymes (3)

Prolonged antibiotic use disrupts the gut microbiome, leading to diarrhea, bloating, and food sensitivities. Bacillus subtilis is a powerful spore-forming probiotic that:

• Restores beneficial gut bacteria that antibiotics destroy.
• Produces protease and amylase, enzymes that help break down proteins and carbohydrates for better digestion.
• Supports detoxification pathways, assisting the liver in clearing out toxins released by Lyme bacteria and its die-off process (Herxheimer reaction).

Since Bacillus subtilis can survive harsh stomach acid, it reaches the intestines intact, ensuring maximum effectiveness.

Bifidobacterium bifidum – Strengthens Gut Barrier & Reduces
Autoimmune Reactions (1,2)

Many Lyme sufferers experience autoimmune-like symptoms, where the immune system starts attacking healthy tissues. Bifidobacterium bifidum helps by:

• Strengthening tight junctions in the gut lining, preventing harmful substances from entering the bloodstream.
• Regulating immune function, reducing overactive inflammatory responses that worsen fatigue and pain.
• Improving digestion of fiber and complex carbohydrates, preventing bloating and irregular bowel movements.

A strong gut barrier prevents toxins, undigested food particles, and bacteria from triggering widespread inflammation.

Bifidobacterium longum – Reduces Neuroinflammation & Supports
Cognitive Health (1,2)

Brain fog, poor memory, and mental fatigue are common in Lyme disease due to neuroinflammation. Bifidobacterium longum helps by:

• Producing short-chain fatty acids (SCFAs) that reduce inflammation in the brain.
• Modulating the gut-brain axis, improving focus, mood, and energy levels.
• Protecting against stress-induced anxiety and depression, which often accompany chronic illness.

By restoring balance in the gut-brain connection, this strain can help improve mental clarity and emotional well-being.

Lactobacillus acidophilus – Balances Gut Bacteria & Supports Immune
Function (1,2)

Lyme disease often leads to an overgrowth of harmful bacteria in the gut, causing digestive discomfort, yeast infections, and weakened immunity. Lactobacillus acidophilus helps by:

• Producing natural antimicrobial compounds that prevent pathogens like Candida and Clostridium difficile from taking over.
• Enhancing the body’s ability to absorb nutrients, ensuring essential vitamins and minerals reach cells for proper function.
• Boosting immune responses, helping the body fight infections without excessive inflammation.

This strain is essential for gut balance, reducing unwanted bacterial overgrowth while strengthening the body’s natural defenses.

Lactobacillus bulgaricus – Supports Gut Motility & Reduces Constipation (1,2)

Digestive sluggishness, bloating, and constipation are common in Lyme disease due to nerve dysfunction and gut microbiome imbalances. Lactobacillus bulgaricus plays a role in:

• Stimulating gut motility, preventing constipation and slow digestion.
• Breaking down lactose and proteins, making dairy and protein-rich foods easier to digest.
• Promoting the growth of other beneficial probiotic strains, enhancing overall gut health.

This strain helps restore proper gut movement and nutrient absorption for Lyme sufferers with
irregular digestion.

Lactobacillus casei – Regulates Immune System & Lowers Inflammatory Responses (1,2)

Lyme disease triggers widespread immune dysregulation, making it difficult for the body to
fight infections while avoiding excessive inflammation. Lactobacillus casei helps by:

• Supporting immune tolerance, preventing the body from attacking its own tissues.
• Reducing inflammatory cytokines, which are responsible for joint pain and fatigue.
• Enhancing gut microbial diversity, which improves digestion and overall health.

This strain particularly benefits immune system balance, ensuring the body fights Lyme effectively while preventing excessive inflammation.

Lactobacillus plantarum – Fights Harmful Bacteria & Supports Digestive Comfort (1,2)

A disrupted microbiome often leads to overgrowth of harmful bacteria, causing bloating,
diarrhea, and food intolerances. Lactobacillus plantarum is known for its ability to:

• Survive harsh stomach acid, ensuring it reaches the intestines intact.
• Produce antimicrobial compounds that suppress harmful bacteria like E. coli and Staphylococcus.
• Reduce gut inflammation, improving symptoms like IBS, diarrhea, and abdominal pain.

This strain helps restore gut balance and improve digestion by keeping harmful microbes in check.

Lactococcus lactis – Enhances Digestion & Produces Essential Nutrients (1,2)

Many Lyme sufferers struggle with poor digestion and nutrient absorption, leading to
deficiencies in vitamins and minerals. Lactococcus lactis contributes by:

• Aiding in the digestion of lactose, proteins, and carbohydrates, preventing bloating and discomfort.
• Producing B vitamins and lactic acid improves energy production and metabolic health.
• Strengthening the intestinal barrier, preventing toxins from entering the bloodstream.

This strain is important in nutrient metabolism and gut integrity, supporting overall recovery.

Saccharomyces cerevisiae – Prevents Antibiotic-Associated Diarrhea & Fungal Overgrowth (1,2)

Prolonged antibiotic use often leads to diarrhea, yeast infections, and gut imbalances. Saccharomyces cerevisiae, a beneficial yeast, helps by:

• Preventing antibiotic-associated diarrhea, restoring normal bowel movements.
• Competing with Candida yeast, reducing the risk of yeast overgrowth and infections.
• Supporting detoxification, helping remove toxins produced by Lyme bacteria.

This probiotic benefits those who experience recurrent yeast infections and antibiotic-related gut issues.

Streptococcus thermophilus – Aids Digestion & Reduces Gut Inflammation (1,2)

Food sensitivities and digestive discomfort are common in Lyme sufferers. Streptococcus thermophilus helps by:

• Breaking down dairy proteins, reducing bloating and intolerance symptoms.
• Producing anti-inflammatory compounds, which help soothe gut irritation.
• Supporting gut flora balance, preventing harmful bacterial overgrowth.

This strain helps restore digestive comfort, making it easier to enjoy a broader range of foods without issues.

How to Use LP3 Probiotics for Lyme Recovery

For Lyme sufferers, consistent use of probiotics is essential for long-term benefits. LP3 Probiotics is easy to incorporate into a daily routine:

1. Start with a small dose – 1 teaspoon per day mixed in water or juice.
2. Gradually increase to 1–2 tablespoons per day for more potent effects.
3. Take it before or with meals to enhance digestion and nutrient absorption.
4. Use it daily for at least 30–60 days to experience noticeable gut and immune
   improvements.

Unlike pills, this liquid probiotic is immediately bioavailable and starts working immediately.

Why the POWER of 3 with LP3 Probiotics Stands Out

• More effective than freeze-dried probiotics – Live, liquid formulation ensures higher survival rates in the gut.
• Contains postbiotics – These naturally fermented nutrients support gut healing and immune function.
• USDA Certified Organic, Non-GMO, and Vegan – Free from artificial additives and gut irritants.
• Safe for all diets – Suitable for Paleo, Keto, Vegan, and Low-FODMAP diets.
• No added sugars, sweeteners, or preservatives – Just pure, beneficial bacteria.
• Made in an FDA-registered facility in the USA – Ensuring quality and safety.

Final Thoughts

Lyme disease recovery is challenging, but gut health should not be ignored. LP3 isn’t an ordinary Probiotic, it has the POWER of THREE with its uniquely blended PRE-PRO-POST biotic combination excels in providing a powerful solution for rebuilding the microbiome, reducing inflammation, and improving digestion. And, paired with the quantum leap results that we have seen for our Lyme disease customers with LP2: you’ve got the best chance possible to lead a life well worth living!

With 11 live probiotic strains, bioactive postbiotics, and a liquid formulation that works faster than traditional capsules, this supplement offers a practical and effective way to support the body’s healing process. For those struggling with fatigue, digestive issues, joint pain, and immune imbalances, adding LP3 Probiotics to their daily routine could significantly affect how they feel.

References:

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2. Chen, Jun, Xinyi Chen, and Chun Loong Ho. “Recent development of probiotic
   bifidobacteria for treating human diseases.” Frontiers in bioengineering and
   biotechnology 9 (2021): 770248.
   https://pmc.ncbi.nlm.nih.gov/articles/PMC8727868/ 
3. Schwan, Tom G., et al. “GlpQ: an antigen for serological discrimination between
   relapsing fever and Lyme borreliosis.” Journal of clinical microbiology 34.10 (1996):
   2483-2492.
   https://pubmed.ncbi.nlm.nih.gov/8880505/ 
   Richards, Crystal L., et al. “The arginine deaminase system plays distinct roles in Borrelia
   burgdorferi and Borrelia hermsii.” PLoS Pathogens 18.3 (2022): e1010370.
   https://pmc.ncbi.nlm.nih.gov/articles/PMC8947608/